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Built for researchers and life sciences teams
OpenFold3 on Vultr runs on AMD Instinct™ GPUs, giving researchers a production-ready protein structure prediction service without managing infrastructure.
Get started with OpenFold3 on Vultr
A few steps to go from a Vultr Kubernetes cluster to a running protein structure prediction service.
Get started with the
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Powered by AMD Instinct™ GPUs on Vultr Kubernetes Engine
Run OpenFold3 on Vultr Kubernetes Engine
OpenFold3 is an GPU-accelerated protein structure prediction model that predicts the 3D structure of proteins, nucleic acids, and small molecules from sequence data, running on AMD Instinct™ GPUs for high-throughput structural biology predictions.




AMD GPU Acceleration
Runs on AMD Instinct MI3xx GPUs via AMD Inference Microservices (AIM), delivering high-throughput protein structure predictions at scale.
Multi-Chain Input Support
Submit proteins, RNA, DNA, and ligand chains in a single prediction job with full multi-entity structure support.
Flexible MSA Alignment Modes
Choose from No MSA, ColabFold server alignment for higher accuracy, or upload a custom .a3m file for full alignment control.
3D Structure Visualization
Predicted structures render interactively in the browser with JSON output available for downstream analysis.
Deploy AMD AI Workbench
Start with AMD AI Workbench on VKE. It provisions the shared gateway, GPU Operator, and certificate manager that OpenFold3 requires.
Deploy OpenFold3 on AMD AI Workbench
OpenFold3 VKE Application deploys on your existing AMD AI Workbench cluster, with automatic HTTPS and model hosting included.
Deploy an AMD Inference Microservice
Deploy AMD Inference Microservices from the AIM Catalog on your AMD AI Workbench cluster with OpenAI-compatible endpoints.
Deploy a VS Code Workspace
Launch a VS Code workspace on AMD AI Workbench preconfigured with PyTorch, TensorFlow, and ROCm on AMD Instinct™ GPUs.
One-Click VKE Deployment
Deploy directly from the Vultr Marketplace with no additional infrastructure setup.
AMD GPU Acceleration
Runs on AMD Instinct™ GPUs via AMD Inference Microservices (AIM) for high-throughput predictions.
Flexible MSA Alignment Modes
Choose from No MSA, ColabFold server alignment for higher accuracy, or upload a custom .a3m file for full control over alignment.